I had 2 Reclast infusions over the last 4 years because I cannot take the pills. My mother and grandmother broke their hips without falling because of osteoporosis. Healthy incredibly active women who ate a huge amount of green leafy vegetables & exercised daily over decades and still ended up with it. My sister walks 2 hours a day and does yoga and now at 64 has osteoporosis. I had undiagnosed celiacs for decades so I was being malnourished without knowing it, so I am now being treated for bone loss. After my first Reclast infusion, I had flu like symptoms for 3 days. Before the second infusion I was told to take an Advil before the infusion and one when I got home. I was just a bit achy. I saw no increase in my bone mass in the first two years BUT I HAD NO BONE LOSS. In the third year my score increased by 3 points. I will need to do Reclast again next year to keep my bone mass where it is. Good luck with your choice!