Hi again,

Gosh, your Metoprolol dose is very high, and I've never heard of the high dosage, especially twice daily. The morning after taking my first Metoprolol, I woke up at 0300 fully rested, whereas before that, I slept until 0830, then still felt exhausted. I was puzzled at first, then remembered that I'd taken the first pill the night before, so I got up and Googled it, and it said that the drug could work in about two hours. You're making a smart move by holding off until you can confirm the dosage. Good luck to you. My VA doctor is much better than my other two private practice doctors, who always seem to be in a hurry to get the next patient.