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Dosage Adjustments On Tymlos Pen

Osteoporosis & Bone Health | Last Active: Dec 8 12:46pm | Replies (143)

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@jmla

Hi All - I am new to this forum. I’m so happy to have found all of you. I’m sorry if this is a late post, but I just started Tymlos about 10 days ago. I took the full dose for two days and had major side effects so I had to drop to 40mcg. I still had some symptoms at 40 (tachycardia for 15 min., headache, fatigue), but they are much more manageable and have almost gone away over the last week. One benefit of injecting at night for me is that I sleep like a log! (I have not slept this well in years.) My doctor wants me to stay at 40mcg until my first blood test to see if that dose is adequate for me. I am 5’3” and 110 lbs. I would like to click up to 50 mcg, but my doctor asked me to stay at 40. He said the drug would still work and he doesn’t want me having side effects. Like many of you, I would tolerate the side effects for better bones at the end of two years. Does anyone know if there are studies about the effectiveness of half the regular dose of Tymlos?

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Replies to "Hi All - I am new to this forum. I’m so happy to have found all..."

Hi @jmla I'm taking Forteo, an almost same drug as Tymlos, although forteo only has one dose which is 20mcg. Our ht and wt are similar though I am just a bit heavier than you so I thought to give you what I experienced. For the first month and a half, I experienced low blood pressure all day long, as low as 80/50, which made me not wanting to get out of bed and lots of fatigue during the day. I didn't do much of exercise either during that period. I didn't experience headache or tachycardia. Low blood pressure is a known side effect of pth and tachycardia could occur as a compensatory mechanism. So you might to check your blood pressure. My endo asked me to drink 10-12 cups of water daily, and if needed, adding some salt to water. Gradually my body got used to the med and second month was a lot better! Now I didn't feel anything. Hope this helps

What blood test will show if dose is adequate? Thanks

@jmla I am sensitive to meds and could not tolerate Forteo. I am the exact same size and weight as you. I got up to 6 or even 7 clicks over time with Tymlos and had excellent gains. If you are tolerating 4 clicks I think it is reasonable to go up to 5. Do you need your doc's permission? My doc let me do whatever I wanted and could tolerate. I think side effects are kind of up to us, but effectiveness is the doc's responsibility 🙂