From everything I’m reading from various sources, Factor V Leiden is an inherited condition passed from one parent, and rarely, though possible, from both parents. I couldn’t find anything to indicate this could be an acquired mutation.
So…if that’s the case…somebody has some ‘splainin’ to do. 😉 I’m sure you’re scratching your head now.

A few questions for your hematologist; Can a person have Factor V Leiden with no familial history? Can it be an acquired mutation?