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@loribmt

The next generation sequencing results will be helpful for your doctor to gather more genetic information about your CCUS status and what’s contributing to your low blood counts. Some of these blood conditions can develop very slowly over many years before anything significantly changes.

Since you’ve had up and down numbers for close to 30 years it may be possible there are some changes taking place now.

You may have had progression for some time but it wasn’t until you injured your leg that it became apparent. If you had an infection or injury that didn’t heal quickly that could have been an indicator that your immune system wasn’t at 100%. That same deficiency can be the reason your body reacted the way it did with the Influenza A, having to be hospitalized and now, not recovering very quickly.

Are you working with a hematologist?

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Replies to "The next generation sequencing results will be helpful for your doctor to gather more genetic information..."

I have received my NGS results. Official diagnosis is
CCUS. My understanding is from an article I read is they don’t really know whether to treat it or not. Mine is a continue to monitor case. Mayo will do more bloodwork in March and discuss the pros and cons of a bone marrow transplant IF it’s even needed. And that’s a huge
If. At my age I may never need that procedure.
Seeing as how I’ve had this for probably over 30 years.
CCUS may not even be the issue. Time will tell. I feel fairly confident that I can squeeze in another 15 or 20 years.
https://ashpublications.org/ashclinicalnews/news/6306/Clonal-Cytopenia-of-Unknown-Significance-To-Treat