I take 800mg 3x a day, spaced roughly at 10pm, 8 am, 3pm. (It works for me to allow more time between night/morning doses and a little shorter time between day doses so I can be at peak performance when I need it a little more - when I’m awake, active & exerting myself, and possibly affected by unavoidable temperature changes outside or in air conditioned places). I started 7 years ago at 100mg and it took about 6 months to find that my 800 mg dose gave me the most constant and consistent pain relief. If I miss my late afternoon dose, my body almost always lets me know within 2-3 hours as internal leg nerve pain will start to surface. It helps a lot with the uncomfortable cold & heat my hands/feet can have; it helps a lot with tingling too, but does not help me with numbness. I know most folks take a lot less and works for the comfort level they need.

Taking 600 twice a day. Has not helped PN