osteoporosis, calcium supplements and calcium paradox

Posted by melia7 @melia7, Mar 9, 2023

Hello, I am prescribed to take alendronic acid with vitamin D3 for my osteoporosis. I take also calcium 1000mg for a long time. However, I have also high cholesterol (about 6,9) and I wonder about negative effect of such medication on my blood vessels. I have searched the literature and found that osteoporosis itself can cause calcification of vessels. Calcium supplements are found in some articles to cause the progression of aorta calcification. So, the question is if your doctors are recommending you to take calcium supplements or not?

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@melia7

Hello rhubymama,

the link that you posted is very illuminating! I have read the article by Schwalfenberg and feel now that my decision about the therapy is more autonomous. Thank you so much. I worked as a biochemist in the past and it help me now a lot to understand articles. The mentioned article claims that the joint action of vitamin K2 and calcium can have comparable effects to the therapy by bisphosphonates. My mistake was that because of my high cholesterol I excluded foods containing vitamin K : butter, yolks, many animal products.

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@melia7 I read vitamin k1 mainly are from green leafy, while vit k2 are mainly from fermented food. like you I have cholesterol problem, so I just eat sticky natto to get enough k2 to avoid full fat dairy and cheese

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@mayblin

@melia7 I read vitamin k1 mainly are from green leafy, while vit k2 are mainly from fermented food. like you I have cholesterol problem, so I just eat sticky natto to get enough k2 to avoid full fat dairy and cheese

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in reply to @mayblin
I take the complex: vitamin D3 and vitamin K2 (75 microgram). At the same time I buy dairy products with 0 fat: kefir, cheese and light mozzarella. What kind of natto do you take? What dose?

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@melia7 I see. I drink a serving of kefir daily also, with occasional a slice of cheese in my sandwich. read that gouda has higher content of k2 and it tastes good, my opinion. natto is sticky and stinky! my current brand is 'shirakiku', ~1 tablespoonful is enough for a day I think ~1/4 of the little white container. I felt brand is not important just make sure they are made in Japan, and organic if available.

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Check out “ vitamin K2 in the calcium paradox” by Dr. Kate Rheaume-Blue.

Well written.

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First, you can get your coronary artery calcium tested with a scan that will show how much plaque is already in your arteries. It might not be a bad idea because osteoporosis can be correlated with calcified arteries. Calcium from broken down bones is readily deposited in soft tissue. Note that it is important to take adequate calcium so that what is in your bones stays there and does not move into your arteries. It could be that your arteries are clear so your osteoporosis should be your highest priority; it probably poses a greater risk anyway. My cholesterol is high and I have zero calcium in my coronary arteries, as do 5% of people over 70 like I am. Second you should not take more than 900 mg of calcium from supplements a day, and get the rest from food. Each dose should preferably be no more than 300 mg and certainly no more than 400mg. Some sources say that 500 mg is the limit, but it is better to be conservative and the idea is not to spike your serum calcium, which will prompt your body to reduce it by depositing calcium in your soft tissues rather than using it to remodel your bones.

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@melia7

in reply to @mayblin
I take the complex: vitamin D3 and vitamin K2 (75 microgram). At the same time I buy dairy products with 0 fat: kefir, cheese and light mozzarella. What kind of natto do you take? What dose?

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Do you take MK4 or MK7? And are the two together? Supposedly the MK7 is better.

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@cpd54

Do you take MK4 or MK7? And are the two together? Supposedly the MK7 is better.

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No, here is only Mk7 available, so I have to take it.

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reply to 06111945cc
I have ordered the book by Dr. Rheaume-Blue, and also have found useful article about the demonstrated K2 effects on osteoporosis. Very precise and easily understandable:
https://journals.indexcopernicus.com/api/file/viewByFileId/921825.pdf

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@cpd54

Do you take MK4 or MK7? And are the two together? Supposedly the MK7 is better.

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@cpd54 I try to get k2 naturally from food. but there is a brand 'innovixlabs' on Amazon which has both mk4 n mk7. I took the pills if I travel. my doctor said the studies on vitk2 are inconclusive

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I used to take very high dose Vitamin K2 but started using Tymlos and I asked whether they compatible. I was told not to but feel that I should still take at least a smaller dose. Has anyone received medical advice about using K2 or MK 4 or 7 with Tymlos or even Forteo?

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