@irenea8 with breath activation off I found that the Aeroeclipse XL took about 20 minutes. The Sprint reusable, which also works inline with Ombra and aerobika cut down the time to between 10-12 minutes, so almost half. Since I have a few Aeroeclipse XL on hand, from now on I'm going to buy the Sprint reusables. Spending the time, whether 12 or 20 mins nebbing saline, I think might be necessary to get the saline distributed throughout the lungs but I don't know for sure!