Treatment for Prostate Cancer Metastasized to Bones

Posted by cal77 @cal77, Aug 27, 2023

4 months ago diagnosed with Prostate Cancer that has Metasized into Bones. So far, just getting Hormone Treatment...Eligard and Erleada....Feeling so tired...Is this normal? Is there any other treatment available?

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

@melcanada

They have not done my PSMA scan for eligibility yet and clinical trial closing soon They say branch of trial is random If chemo I would stay local hospital and not do trial. I see you can travel 3 days after and if flying must notify TFSA
Did they talk survival with you and what was said?
This if interesting I am Stage 4 in bones L2 T10 11 moving up T 76 7 but very small load But 2,3 x 2,3 in upper chest bone L1 was radiated out in 2020
Where is yours ?
Of great interest
https://airomedical.com/blogs/articles/lutetium-177-psma-therapy-everything-you-need-to-know#what-is-the-success-rate-of-lutetium-177

Jump to this post

Mine is in totally different areas than yours and our age and our journeys are totally different so don’t think our prognosis would be comparable. 2-5 years is what I was given by the chemotherapy doctor but has not been discussed with the Pluvicto team. What I can tell you about Pluvicto as they told me the success rate is as follows:
33% do very well
33% mediocre
33%fail

REPLY
@round5

Mine is in totally different areas than yours and our age and our journeys are totally different so don’t think our prognosis would be comparable. 2-5 years is what I was given by the chemotherapy doctor but has not been discussed with the Pluvicto team. What I can tell you about Pluvicto as they told me the success rate is as follows:
33% do very well
33% mediocre
33%fail

Jump to this post

Are you Stage 4? Where is cancer? How old are you pls? Were you on Xtandi /Enzalutamide?

Did you get a chance to see success rates here
https://airomedical.com/blogs/articles/lutetium-177-psma-therapy-everything-you-need-to-know#what-is-the-success-rate-of-lutetium-177

REPLY

Yes
Shoulder, lymph nodes and retroperoneal
65
No
Yes

REPLY

I had 3 infusions of Pluvicto and had to stop it. No side effects except that my PSA started out at 1.56 and ended up at 20.83 after the 3rd. I'm interested to see if anyone else had this problem. I'm now on Jevtana and Carboplatin at the same time. My PSA is fluctuating around 20 now. It has started to rise by 1 to 2 points every 3 weeks. Much slower but concerning. This is the second go around for Jevtana. They added Carboplatin along with it. No side effects but a little fatigue. Biggest problem besides the PSA is the Nuelasta shot to bring up the WBC. It's giving me body aches for up to 7 days. I'm trying various combinations to combat that, any advice would help. I feel pretty much normal for 2 weeks every month. Anyone that wants to know my journey just ask. I'm going on my 10th year of the battle. I'm 62 years old now and I will never give up.

REPLY
@baxterlee77

How are you doing today? Russ had to stop the abratone ! Said his Psa went up 😞 he is on XTANDI !very nasty drug

Jump to this post

I was on Xtandi for 3 months. My PSA started rising and by the 3rd month I needed help to put my jacket on and sometimes needed help to get out of the chair. A few months later after stopping it I was back to normal and needed no help.

REPLY
@round5

I actually had quad therapy since they added the Carboplatin. I am now a few months past that. My post scans still showed the spots but they were smaller. He was unsure whether it was still active cancer or just the so called scar tissue of dead cancer cells. We could have just stopped and waited for another scan in a few months to see or hit it with a 5th. medication. He recommended the latter and gave me the choice and I chose to continue with the Pluvicto. I have completed 2 of the 6 doses. They will do a scan immediately prior to the 4th.dose then based on that scan we’ll decide whether to proceed with 5 and 6. If the scans show the cancer is gone or if it shows the Pluvicto is not working then I’ll probably not receive the 5th and 6th doses.

Jump to this post

Keep a close eye on the Pluvicto. I had to stop after the 3rd round. My PSA started out at 1.56 and ended up at 20.83. I might be a rare case on that one, so chances are it will help you.

REPLY
@robert570

Keep a close eye on the Pluvicto. I had to stop after the 3rd round. My PSA started out at 1.56 and ended up at 20.83. I might be a rare case on that one, so chances are it will help you.

Jump to this post

I was undetectable when I started treatment and have remained that way. I was one of those with metastatic disease and very low to undetectable PSA. Was only 0.62 when scan showed metastatic disease and I got the chemo however even after that there were still some spots left so we proceeded with the Pluvicto. So many people think just because they have an undetectable PSA there is no cancer and most of the time that is the truth, but not always.

REPLY
@robert570

I was on Xtandi for 3 months. My PSA started rising and by the 3rd month I needed help to put my jacket on and sometimes needed help to get out of the chair. A few months later after stopping it I was back to normal and needed no help.

Jump to this post

So what drug do u take now instead of XTANDI ? 😊

REPLY

I'm on Jevtana and Carboplatin chemotherapy. 2 chemo infusions the same day with no side effects. Jevtana targets prostate cancer cells only and I don't have have hair loss. Its more of a milder one. The Carboplatin is supposed to help with that. Im in such good shape, I can handle both together. The only problem now is I have to get the Nuelasta shot to raise my WBC the next day and it causes me body aches for a week.

REPLY
@robert570

I'm on Jevtana and Carboplatin chemotherapy. 2 chemo infusions the same day with no side effects. Jevtana targets prostate cancer cells only and I don't have have hair loss. Its more of a milder one. The Carboplatin is supposed to help with that. Im in such good shape, I can handle both together. The only problem now is I have to get the Nuelasta shot to raise my WBC the next day and it causes me body aches for a week.

Jump to this post

How many days will you be on please? Is this a clinical trial or just recommended?
Did you stat this to replace Xtandi?
They want me on C trial for 177 or chemo with cross over if one does not work Would rather not drive 2 hours when I can get chemo in local hospital PSA 4.5 bot C creeping up T 7 8 9 10
Praying for better out comes with this stage 4 since 2020 when I had L1 radiated

REPLY
Please sign in or register to post a reply.