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@cutlermax

I also have chronic microvascular disease, In English what does " Subcortical and periventricular white matter T2/FLAIR signal abnormality in keeping with sequela of chronic ischemic microvascular change" Mean? At what stage of the disease? location? What? Neurology consultation with Scott Speelziek, M.D. end of December, hear anything about him? I have been asked to join Mayo Clinic's Tapestry Study, Tapestry: Genomic Sequencing in Clinical Practice. I don't know why they chose me. What the hack. it only helps me or maybe someone else.

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Replies to "I also have chronic microvascular disease, In English what does " Subcortical and periventricular white matter..."

I have CMVD as well. From researching my own situation it appears that the areas affected in your situation (similar to my own) are associated with memory, balance, and mobility. Are you symptomatic? The second part of the statement just indicated that it is an ongoing process, which is to be expected with this disease. Have you had more than one MRI? Subsequent MRI's can show any progression of the disease. In my case they are able to quantify the number of lacunar strokes due to the CMVD. It will be interesting to see what they say at your consultation, please keep us posted. Good luck!

@cutlermax, it sounds like you have received some test results before having a chance to review them with a physician. That can be nerve wracking.

You mention the Tapestry Study. A few other members are talking about taking part in it here:

- Anyone participating in the Tapestry DNA Sequencing Research?
https://connect.mayoclinic.org/discussion/anyone-participating-in-the-tapestry-dna-test/
.
- Tapestry Results are In, What is your story?
https://connect.mayoclinic.org/discussion/tapestry-results-are-in-what-is-your-story/