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Is there a connection between b6 toxicity and thyroid issues?
Diabetes & Endocrine System | Last Active: Dec 20, 2025 | Replies (21)Comment receiving replies
I have the EXACT problem. B6 toxicity from food alone and have hypothyroidism. Your story sounds exactly like mine. I tried cutting back on b6 foods, done tons of labs, taken tbyroid medication, etc. I’ve posted my journey on a Facebook group.
I believe I have a rare form of hypothyroidism called central hypothyroidism that is driving it.
I also have peripheral neuropathy
Anyway we can connect to compare notes and try and find a solution?
If links are allowed I could send you my documented journey and comments from the Facebook group.
Replies to "I have the EXACT problem. B6 toxicity from food alone and have hypothyroidism. Your story sounds..."
I was diagnosed with high B6 toxicity 20 months ago. I follow a protocol from a FB group eating the RDA of b6 daily and working on not going under or over it. I’ve recently developed irregular heart beat (I’ve had this is the past), my neuropathy is worse and I am checking out my thyroid. No matter what I eat my face starts tingling. I am really not feeling well.
@proudx Hi, recently going thru the same. My health has had odd stuff my whole life. My recent labs: FB6. 605.2. No that is not a typo. It’s a toxic level of B6. My B12 level is also very high. I noticed a trend in prior labs with consistently low Alk Phos levels. Research indicated that I should check B6. It began. I now know I have Hypophosphotasia. HPP. If you have consistently abnormal low alk phos, have your B6 tested. If very high. Genetic testing confirms dx. It is a metabolic issue. I have been to urgent care, ER, and cardiologist. They all know of no treatment except advice to D/C any vitamins, avoid any B vitamins in foods, energy drinks and anything else.
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Hello @proudx, I would like to add my welcome to Connect along with @lbishop and others. New members are not able to post links for a short period of time to prevent advertisers from spamming our discussions. You might also be interested in the discussions started by @akalsas and @2luckyppl who also mentioned central hypothyroidism:
--- Central hypothyroidism: https://connect.mayoclinic.org/discussion/central-hypothyroidism/
--- Help! I have a new diagnosis of Pituitary/adrenal insufficiency,: https://connect.mayoclinic.org/discussion/help-i-have-a-new-diagnosis-of-pituitaryadrenal-insufficiency/