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Anyone take a Treatment Holiday? Intermittent use of ADT (hormone Tx)
Prostate Cancer | Last Active: Oct 10 5:53pm | Replies (36)Comment receiving replies
Valid question, here is video that might be of interest...
https://www.urotoday.com/video-lectures/nccn-prostate-cancer-guidelines-review/video/2295-intermittent-vs-continuous-adt-for-patients-a-review-of-the-nccn-guidelines-christopher-wallis-and-zachary-klaassen.html
When reading about Orgovyx...
Advise patients to take a missed dose of ORGOVYX as soon as they remember. If the dose was missed by more than 12 hours, patients should not take the missed dose and resume with the next scheduled dose. | If treatment with ORGOVYX is interrupted for greater than 7 days, restart ORGOVYX with a loading dose of 360 mg on the first day, and continue with a dose of 120 mg once daily. (https://www.drugs.com/dosage/orgovyx.html)
I am on ADT (Eligard + Zytiga) and there is no practical way to take a holiday from the drugs. The Eligard is a 3-month injection and the Zytiga can easily be skipped and would just make a small improvement in QOL. For me personally, managing the side effects through the holidays equates to getting plenty of sleep, exercising daily, and avoiding sugary foods. The brain fog from these drugs is my biggest QOL issue, and eliminating sugar has done wonders to reduce the fog.
Last but not least, always enjoy holiday and family traditions. Those are memories and experiences that are meant to be cherished and enjoyed. I will eat a peperoni pizza and chocolate cake with my family even if it shortens my life, the smiles and warmth of family and friends is why we are here.
Replies to "Valid question, here is video that might be of interest... https://www.urotoday.com/video-lectures/nccn-prostate-cancer-guidelines-review/video/2295-intermittent-vs-continuous-adt-for-patients-a-review-of-the-nccn-guidelines-christopher-wallis-and-zachary-klaassen.html When reading about Orgovyx... Advise..."
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I appreciate your post greatly; as that video gave me the most information (more than three docs and two radiation oncologists); only one of which would even acknowledge the topic of 'drug holidays' or intermittent. In my case I've had a pacemaker installed and probably didn't need it, as the irregular heartbeat (bracycardia) might have been triggered by too long ADT.
I was on Orgo. for 15 months and never was it mentioned as a 'course of treatment you stop' at a point or IF there are side effects. I had many of the side effects and stopped taking it on my own and almost all normalized. BUT, the PSA popped back up so starting it again and we'll test in 3 months.. even another PET scan. Due to cardio-drugs I didn't think brain fog was a factor, but now that you mention it, maybe I can attribute the 'fog' to the ADT treatment not Blood Pressure treatment or statins.
I knew about the re-loading to restart and followed that (thanks); but mostly for that video; 2 years old and far more informative than any information I've encountered on this topic. Cheers and good luck to you too!