Good evening @hillclan, nice to meet you. I am happy to share my Alendronate story with you. After two years on Tymlos.....building bone and being free of any side effects, my endocrinologist told me I had to go on Prolia. That was not a good idea and after a year I was suffering with jaw pain and other side effects. With the support of my PCP, I found a new endocrinologist at Mayo Clinic. He reviewed all of my medical history and recommended Alendronate. Instead of a twice-a-year infusion of Prolia which had a long half-life, the Fosamax is a tablet that I take every Monday morning. I follow the directions carefully and then begin my week.

It has been 18 months now and I have had no issues, discomfort, or side effects. In June of 2024, I will discover how well my bones have held onto the development I received from two years on Tymlos. The Dexa scans will reveal what I am anxious to see.

It seems that my body can handle daily Tymlos injections and weekly Alendronate tablets. It just can't handle large infusions of any medication.

So...positive is exactly how I am feeling. And may you also be safe, protected, and free of inner and outer harm.

Chris