I have been to the Mayo Clinic twice now. They are the only ones that have given any hope what so ever. (Two urologists in OK told me there wasn't anything they could do to help). Mayo says they can do a procedure called a HolEP, there's only 2 Drs at Mayo that do this procedure. Can't get in until July-August. They would router out the inside of the prostate (mine is severely enlarged as well). The doc said it would in time, reduce my self cath from 4 times a day to one or two times a day. Healing time approximatly 3 months, of course, there are side effects.... My family physician referred me to Mayo. I would like to talk to someone that has had this done!!