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@markymarkfl

@scalettasandy That's not a stupid question at all. There are various studies out there suggesting compression and cooling MAY help.

Numerous solutions are available with socks/booties etc that have slots for ice packs, some that provide compression, and some that provide both.

Appropriate gloves might be harder to come by, but one study saw good results from compression alone, using two surgical gloves (one layered on top of another) one size too small on each hand. I've tried this, and it's a lot more enjoyable than icing.

The theory is that cold and compression constrict blood vessels, restricting blood flow. If you ice and compress while the worst chemicals (abraxane, platinum) are being infused and for a little while after, you avoid the strongest concentrations of those drugs being delivered to your periphery (hands and feet) and thus to the nerves in that area. It seems like elevation would help as well, but I haven't seen any literature on it.

A similar approach using cold caps during chemo has been somewhat effective at reducing hair loss.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810270/
https://www.curetoday.com/view/cold-compression-may-prevent-chemo-induced-neuropathy

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Replies to "@scalettasandy That's not a stupid question at all. There are various studies out there suggesting compression..."

Thank you for taking the time to respond. It seems every time at try to investigate things that I hear that happens to pancreatic cancer patients the more panicked I become! I can’t sleep because it all is so darn scary and painful and I’m all alone here. I’m looking like a walking bald skeleton and to be honest can’t figure out how go on knowing some of the horrendous things coming! I was diagnosed in March and have done nothing but cry, panic , not sleep, can’t eat anything anymore unless I want to spend a couple hours in the bathroom. I just don’t know what to do. I’m sorry, I’m just at the end of my rope how scary this is