Your experience during & after Transrectal Prostate Biopsy (TRUS)

Posted by somi @somi, Oct 19, 2023

Hi, my husband is scheduled for a trans rectal prostate biopsy tomorrow. His PSA has been rising and his urologist recommended it. I’ve read horrible accounts on the internet of complications and I was wondering if anyone would share their experience, both positive and negative. Has anyone had an uneventful recovery? I’m hoping he will delay the procedure until we know more. Thank you and God bless.

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No problem with a rectal biopsy performed after an ultrasound and multiparametric MRI revealed a likely tumor growth on one side of my prostate. As long as a rectal biopsy is performed at a center of excellence with appropriate pre and post bacterial infection risk management, the risk of complications are very low. If the risk is too much, others have provided info on the alternative biopsy procedure.

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@ajpernsteiner

I had the trans rectal biopsy. Had zero pain, maybe a little pinching Zero after problems. Spoke with the urologist all the way through it. The biopsy ended up gleason 10, and since have had 45 radiation and on my 2nd year of Orgovyx. But the biopsy, was easy, no real pain, and no after effects. Hope his goes as well.

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Interested in 2nd year of orgovyx. Taking it now how long does your dr intend to leave you on it?

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@billfarm

Interested in 2nd year of orgovyx. Taking it now how long does your dr intend to leave you on it?

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right now, it is for 2 years. The only issue I have had with it, is hand pain, and of course that does take some hand strength away.

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Earlier this year I had trans rectal biopsies done in office. It was a painful experience for me. Did receive 4 numbing shots in prostate witch hurt to start with. 12 cores taken. Last two were the worst I actually kicked my leg out with pain. I could not sit on tractor for a few weeks afterwards. Slowly got better. I believe I was one of the few that found it pretty painful. That said I needed the test so not regrets except would want some pain pills beforehand. Remember as in my case cancer was diagnosed and removed. That was a high risk cancer according to the decipher test done from samples. So well worth doing. I had painfully recovery from surgery as far as being able to sit up for quite a while but doing well now 4 months post surgery. 0 PSA and happy.

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I had the same procedure and was concerned as well. No complications.

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somi: all good advice above. You might want your husband to get the decipher test which is used by doctors to evaluate aggressiveness of the cancer. The biopsy material is good for a year but it is a viable way to get another alternative "opinion" of the tumor. The Decipher test report is also easy to understand and also indicates whether 1 or more types of treatments are recommended.

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@seasuite

Great to see a team effort on research! When my wife and I were researching biopsies, she found that TPUS (trans perineal) were less likely to cause infection. While the infection rate with TRUS (trans rectal) biopsies is fairly low, about 1 in 100, it drops 5x with TPUS.

I needed to change Urologists in order to get this procedure which also turned out to be a benefit as my new Dr. was highly accomplished and had led in the introduction of new technologies at Stanford Medical. I tolerated the TPUS biopsy well with local anesthesia. There is some minor pain as needles are injected, however, Drs. typically prescribe Ativan to chill you out and it helps with the 'chomping' that is apparent with all types of biopsies.

I had a minor complication that I had had before during a sigmoidoscopy. Vasovagal reaction is the vagal response when stimulation of the vagus nerve causes symptoms such as lightheadedness, sweating, and blurred vision. This can happen because of stress, pain, heat, having a bowel movement, or even standing too long. It passes quickly, but, my wife freaked when the color ran out of my face.

Best of luck!

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I also had the transperineal. I did not want the rectal. Had to twist some arms but got it done transperineal. The infection rate as you mentioned is 2% for rectal biopies and involves serious type of infections that my urologist stated would require hospital stay. The transperinial is 1 in 500 infection rate so minuscule.

Mine was done with anesthesia so not awake or out so much don't remember as I think they use propronol. I would not have event known I had 20 biopsies done after the surgery as no pain no side affects and right back to exercising.

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@bens1

somi: all good advice above. You might want your husband to get the decipher test which is used by doctors to evaluate aggressiveness of the cancer. The biopsy material is good for a year but it is a viable way to get another alternative "opinion" of the tumor. The Decipher test report is also easy to understand and also indicates whether 1 or more types of treatments are recommended.

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Agree. Mine with biopsies was intermediate. Had Decipher and came back low risk. Thus my treatment plans recommendations went from radiation and hormone to radiation only.

If you have it done after your biopsies there is nothing you need to do and does not involve any tests or procedures done on you. They use the biopsies that were taken. A great test kind of expensive buy Medicare and my secondary insurance paid for it.

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@jasonfarmer

Earlier this year I had trans rectal biopsies done in office. It was a painful experience for me. Did receive 4 numbing shots in prostate witch hurt to start with. 12 cores taken. Last two were the worst I actually kicked my leg out with pain. I could not sit on tractor for a few weeks afterwards. Slowly got better. I believe I was one of the few that found it pretty painful. That said I needed the test so not regrets except would want some pain pills beforehand. Remember as in my case cancer was diagnosed and removed. That was a high risk cancer according to the decipher test done from samples. So well worth doing. I had painfully recovery from surgery as far as being able to sit up for quite a while but doing well now 4 months post surgery. 0 PSA and happy.

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jasonfarmer, did they offer the biopsies via transperineal? That is done in the scrotum area and usually with anesthesia. I have my done that way and was asleep so no pain during procedures and no pain or discomfort after procedure. Went back to exercising the next day.

My urologist wanted to do rectally because I had heart failure but I have had it for almost 20 years and no exercise restrictions and many surgeries with anesthesia. So had my heart failure doctor advise urologist that anesthesia was not an issue and thus had it done transperenial.

There is also a 2% risk of serious infection rates with rectal biopsies that would require hospitialization. The transperininal infection rate is almost negligible to mention.

I was told when you have it done rectally when the needles hit prostrate would feel like a bee sting. No thanks I thought the stress would be terrible.

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@jc76

jasonfarmer, did they offer the biopsies via transperineal? That is done in the scrotum area and usually with anesthesia. I have my done that way and was asleep so no pain during procedures and no pain or discomfort after procedure. Went back to exercising the next day.

My urologist wanted to do rectally because I had heart failure but I have had it for almost 20 years and no exercise restrictions and many surgeries with anesthesia. So had my heart failure doctor advise urologist that anesthesia was not an issue and thus had it done transperenial.

There is also a 2% risk of serious infection rates with rectal biopsies that would require hospitialization. The transperininal infection rate is almost negligible to mention.

I was told when you have it done rectally when the needles hit prostrate would feel like a bee sting. No thanks I thought the stress would be terrible.

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No trans perineal was not offered. No trouble was infection at all. Antibiotics were given pills and shot. Through all of this cancer testing and surgery never even had any infection with the exception of prostatious.

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