Osteoporosis treatment

Posted by mmodestti @mmodestti, Apr 5, 2023

My osteoporosis has gotten out of hand. In February 2022, I suffered five compression fractures (L1-L-5) and in November, three more (T-10- T-12). Each time I spent 10 to 12 weeks in excruciating pain.
My endocrinologist has suggested starting me on Tymlos for 2 years, and then moving on to Prolia. Has anybody used this medication (Tymlos)? How was your experience?

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hikernurse | @hikernurse | Oct 19, 2023

well I finished evenity 2 weeks ago with very minor side affects. Headache, tiredness and a bit achy for a day or so. Bone density and VFA is tomorrow to see what I did with my -3.0–3.3 spine and hip. I do have 4 different fractures in my past. 2 ribs and each wrist from rather forceful sports injuries over the last 10 years! I’m 67 and worried more about prolia!! I guess my choices are aledronate, reclast or prolia. I’m in it for the long haul so I wonder how that figures in for these choices. Please anyone with suggestions do not hesitate to weigh in. You ALL have been so incredibly helpful and no am very grateful. Cindy

imay | @imay | Oct 19, 2023

In reply to @madeleine40 "I am curious to know why he recommended Tymlos over Forteo. Thank you" + (show)

I am on my third month taking Tymlos. My spine score is -4.9, wrist -5.1, and hip -3.3 and -3.7. I am taking it in part to prepare for a hip replacement. From the comparative studies that I have seen, Tymlos is more effective. I did not notice whether they affect the spine differently, although it is common for one medicine to affect specific bones more or less than other similar ones.

pedsnurse61 | @pedsnurse61 | Oct 19, 2023

In reply to @hikernurse "well I finished evenity 2 weeks ago with very minor side affects. Headache, tiredness and a..." + (show)

Hi Cindy, I am also a Retired RN and am glad you were able to complete your 12 month journey with Evenity. I had to stop after 5 months due to increasing side effects and palpitations. My MD was not at all concerned about all the side effects I had and was just interested in taking my co-payment and billing the Insurance Company for the medication. I choose Alendronate after switching MD's and I am also taking an Estrogen patch low dose. It is a difficult decision to make with what to follow Evenity with. I was scared of Prolia and the huge amount of medication given for Reclast ( to last an entire year). I hope you have good results with your Bone Density test tomorrow. I encourage you to read the book " Great Bones" by R Keith McCormick it is an excellent resource for everyone dealing with OP.

kristie2 | @kristie2 | Oct 19, 2023

In reply to @susanfalcon52 "I’m on Evenity and have been told that I’ll have to take Fosamax after. I’m more..." + (show)

Susan,
I think I would be more afraid of Denosumad ( Prolia ) or Ibandronate sodium ( Boniva ).
I am also going to start hormone optimization with biotech.
I too am faced with starting another med after Evenity. I am only 3 months in so far with Evenity.

madeleine40 | @madeleine40 | Oct 19, 2023

In reply to @imay "I am on my third month taking Tymlos. My spine score is -4.9, wrist -5.1, and..." + (show)

Thank you imay. Does Tymlos have to be refrigerated like Forteo?

imay | @imay | Oct 19, 2023

You can keep the pen that you are using unrefrigerated, although I would not let it get too hot or cold. But if you have more than one box, the others should be refrigerated. I just keep them all in the refrigerator anyway, but at least you could conveniently travel with a pen.

Chris Trout, Volunteer Mentor | @artscaping | Oct 19, 2023

In reply to @susanfalcon52 "I’m on Evenity and have been told that I’ll have to take Fosamax after. I’m more..." + (show)

Good evening @susanfalcon52. I am glad you are taking advantage of a medication that builds new bone. Evenity also is able to protect the bone for you. Please share with me what our fear is if you use Fosamax after your year on Evenity. I took Tymlos for 2 years and now take Fosamax. My experience is good without any noticeable side effects. Next spring I will have my two-year scans. I hope the results indicate that I have more protection from osteoporosis.

When will you have your first follow-up scans?

May you be free of suffering and the causes of suffering.
Chris

susanfalcon52 | @susanfalcon52 | Oct 20, 2023

Artscaping,
I fear Fosamax because I have GERD. I did visit my longtime gastroenterologist yesterday to discuss this with him. He said that the only problem with Fosamax and GERD is if you don’t take it as directed and the pill becomes stuck going down. He also said that once the pill passes through your esophagus it is “clear sailing” and “home free.” I trust him, so will forge ahead with Fosamax when i finish Evenity. I have my 6th injections next week. I think the Evenity shots make me tired the next day, but other than that no problems.

Sue Ellen Murrey | @semurrey | Oct 20, 2023

In reply to @susanfalcon52 "Artscaping, I fear Fosamax because I have GERD. I did visit my longtime gastroenterologist yesterday to..." + (show)

I am so scared to go on bisphosphonates as I have significant TMJ with one disc totally eroded due to clenching. I wear a very expensive mouthguard nightly which helps but at 58 yrs old and needing a few crowns, filings replaced I dread the side effects of these drugs. My doc only mentioned it would help me alleviate risk of curvature, hunch back from letrozole estrogen depletion, etc. I'm only 8 months into Letrozole but know it will get worse. Maybe I can avoid curvature ?? She didn't mention anything related to bones mets. Any advice?