ET complicates things. I was always very high energy until I hit 55. Then the fatigue was often crushing, and I didn't want to do anything. I hated to complain about it because you just get relegated to the postmenopausal nutcase group. But I was spacey, tired, irritable, and didn't want to socialize. When I was diagnosed, the hemo said onset of ET was ... age 55. I felt she knew what she was doing treatment-wise, but she maintained until her retirement that ET was a symptomless disease. So I still keep my trap shut about fatigue and visual problems down at the oncology clinic. My GP was more helpful about symptoms.