Clofazimine is very tolerable. Just make sure to take a very good probiotic a minimum of 4 hrs apart from the meds. The skin discoloration is more like a light bronzing/sunburn. It will fade gradually over months once the medication is stopped. Clofazimine is used in combination with other drugs and is effective. It facilitates the other meds getting into the bacteria and working there. This is not a medicine you should be afraid of.