I agree. With my 1st of injections, I had pain in my arms. I couldn't bear them to touch my sheets, so I couldn't sleep in bed. I had to sleep in a recliner with my arms across my chest. However, for me the 2nd and 3rd set of injections I had in my abdomen with minimal discomfort. What a difference--for me. Just sharing my experience in case it might help someone else.