← Return to Anyone take a Treatment Holiday? Intermittent use of ADT (hormone Tx)

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@ddl

My situation is not exactly what you asked about, but it’s close enough that I thought I would respond. I had RP 2 years ago at age 59. My PSA was 23, Gleason 4+4=8, stage 3 with seminal vesicle involvement. 60 days post RP, my PSA declined to 7. I started intermittent Bicalutamide in dosages between 50-150 milligrams per day. Got my PSA down to 0.23 in 6 months. Then stopped for 2-3 months until PSA rose above 2.0. Now I will be on the bicalutamide for 2-3 months then off for 2-3 months depending on how quickly the PSA rises and falls. I am being treated by a Dr in Mexico City. I go once a year for a PET/PSMA scan and I have two tumors in the prostate bed but no metastasis. My Mexican Dr says I can go on indefinitely like this, but I’m going to see an RO at Miami Cancer Institute in December who uses the MRIdian equipment to see if a cure is still possible. If the RO thinks there is a decent chance, I will go for it. I think the intermittent ADT is better for quality of life than constant ADT, but it’s still bad enough that if there is a reasonable chance of getting off it through RT, I will try it.

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Thank you and good luck.