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@gently

Letrozole can cause high blood pressure. Cartia (diltiazem) can decrease the metabolism of letrozole. Letrozole can cause osteoporosis, but I think the current consensus is diltiazem does not.
Did you have high blood pressure before the Letrozole? Letrozole has a 42 hour half life, so it seems like someone shouldn't be taking both in the same day. Are they both prescribed by the same physician?
This is surface information for me. I don't take either drug, but have looked for a relative. It could be something overlooked by your providers.
I'm unhappy when you have to take a drug to counteract the effect of another drug, but sometimes it is unavoidable.

https://europepmc.org/article/med/37079024

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Replies to "Letrozole can cause high blood pressure. Cartia (diltiazem) can decrease the metabolism of letrozole. Letrozole can..."

Appreciate your reply.

I started out with arrythmias and put on calcium channel blocker Cartia and Eliquis blood thinner by cardiologist for blood pressure April 2022.

Breast cancer diagnosis and surgery in Nov 2022.

Put on Letrozole 3/18/23 after radiation therapy by Medical oncoloist.
DEXA scan May 2023 shows osteoporosis..
Now, from what I have read, 1)the body needs vitamin D and vitamin K to bond together to take calcium from the bloodstream to the bones.
2) The calcium channel blocker does something to part of the calcium to keep it from being transferred with the vitamin D and K to the bones.

3) Vitamin D needs to bond with vitamin K to do this.
But Viamin K is a blood thinner. I can't take vitamin K with Eliquis,
4) So, double whammy. The calcium channel blocker does something to the calcium in the blood. The Vitamin D is useless without K to prevent osteoporosis and get calcium to the bones. That, plus Letrozole causes further osteoporosis.
5) If I could get off the calcium channel blocker and eat foods rich in vitamin K, I might have a chance helping bones to break down and build up naturally.

Any thoughts on this????