PSA after 20 Proton treatments

My 4+3 with pre proton therapy PSA of 8.1 is now 1.2 15 months post radiation.
Readings were 2.7, 2.3, 4.9, 1.7 and 1.2. No hormone therapy.

I am 14 years younger than you. I had proton therapy about three years ago and six months of Lupron treatment. Lupron destroyed me I could barely walk and it was a challenge finding the energy to get out of bed..
All the drugs you quoted work by lowering your testosterone. Some day I may have no choice but ADT but that is the day I start shopping for a Nursing Home.

No affect with Zolodex Feel OK and I have Mets to the spine L2 L1 T10 11
Plus on Xtandi and Xgeva
Trying Turkeyt Tail Mushrooms for immune feel gretaer
http://www.realmushrooms.com

My cancer never spread out of the prostate and my PSA is like .16. I am also on testosterone replacement therapy for over a year. I lift weights and exercise regularly and have lost 60 lbs over a year on the Carnivore diet.
I feel better than I have in twenty years.

I will check out the mushrooms.

Is that 4.9 a typo or a “bounce”?

My doc said a nadir of between 1 and 2 is considered a success. However, this is from Google AI Bard. Keep in mind that the answers given are not always correct. Given the numbers people here at 12 months post radiation are quoting, between 1.0 and 2.0 seems a common nadir.

“There is no single "normal" PSA level after proton beam therapy (PBRT) for prostate cancer. PSA levels can vary widely from person to person, and even from day to day. However, most men who achieve a PSA nadir (lowest level) of 0.2 ng/mL or less after PBRT can expect to remain disease-free.

A PSA nadir of 0.2 ng/mL or less is considered a good PSA level after PBRT. However, some men may have PSA levels that are slightly higher than this and still remain disease-free. Conversely, some men may have PSA levels that are lower than 0.2 ng/mL and still experience a recurrence of prostate cancer.

Other factors that can affect PSA levels after PBRT include:

The stage and grade of the prostate cancer before treatment
The total dose of radiation delivered
The type of radiation therapy used (PBRT or external beam radiation therapy)
The presence of other medical conditions
It is important to discuss your PSA levels with your doctor after PBRT to determine what is considered a good PSA level for you. Your doctor will also monitor your PSA levels over time to look for any signs of recurrence.

If your PSA level rises above 1 ng/mL or 2 ng/mL above your nadir, your doctor may recommend further testing, such as a prostate biopsy, to determine if the cancer has returned.

Here are some general guidelines for PSA levels after PBRT:

PSA nadir of 0.2 ng/mL or less: Good PSA level, most men with this level will remain disease-free.
PSA nadir of 0.2-1 ng/mL: Acceptable PSA level, some men with this level may remain disease-free, but others may experience a recurrence of prostate cancer.
PSA nadir above 1 ng/mL: PSA level that may warrant further testing and monitoring.
It is important to note that these are just general guidelines. Your doctor will discuss your PSA levels with you individually to determine what is considered a good PSA level for you.”

Bounce

artistik1a, Just reading these question. No drugs prior, during, after. Had some reduction in urine flow and dribbling but improved.

I had my proton treatment at University of Florida Proton Therapy Institute. My follow up PSA (just did it week ago) was done at Mayo Jacksonville. Decipher test was done at Mayo Jacksonville. PSMA was at Shands Hospital (Co located with UFPTI).

My primary care doctor who wants to monitor my PSA also orders the tests that UFPTI wants done and UFPTI can view as part of some medical sharing. For my proton treatment follow ups are done at UFPTI.

ozelli, Did you have proton or photon?

Proton