@lengel ...oh that is interesting. About 6 yrs ago and after ibs-d type problems my doctor gave me a cholesterol lowering drug to try, nothing wrong with cholesterol, but caused constipation. I tried it and I remember it cut down about 50 per cent of my trips to bathroom... but inside of moth and tongue etc. got so inflammed, tongue red and cracked and mouth so red and sore, pharmacist was shocked. So i stopped taking it. Not sure how many months later but said could we try again.... we did and same thing happened, so my reaction to drug. Fast forward about 3 months ago and I was referred to a nephrologist and she, upon hearing my woes of fecal incontinence and history, prescribed another such medication ; "LODALIS" (colesevelam hydrochloride) (bile acid sequestrant) to mix with water. But after reading drug info am too scared to try it. Also have sore mouth from previous molar extraction and keep getting bone chips (tiny) coming thru gums which makes mouth sore and also had another molar out yesterday and other side of mouth raw etc. so dare not take any meds I think will cause sore mouth again and am reluctant to tell her I did not try it , next appointment. For 30 single doses it was over $200.00 Canadan, good thing i still have my work health insurance to pay most of it. But I get the idea; find out something that causes constipation and take it for our diarrhea! J.