Can Eliquis lower platelets?

@j68eis There are a number of factors which can influence our blood counts at any given point whether it’s red blood cells, white blood cells or platelets. Our immune system responds to viruses, infections, vitamin/mineral deficiencies, vaccinations, medications, autoimmune diseases, cancers, etc. by increasing or reducing blood products. But they generally rebound back to normal ranges when the event has passed. Occasionally there can be something which triggers a misfire of a normal cell production. Or, it can be from a condition already at play in the body.

You mentioned in a prior comment that you’ve always had fluctuating counts throughout your life. So it’s difficult to know if your lower platelet counts can be attributed to the Eliquis you’re taking, the covid vaccine you inquired about or the infection that you had in the beginning of the year.

I found some articles you might find interesting and helpful, at least to give you more information about how and why platelet numbers fluctuate.
https://www.verywellhealth.com/living-with-low-platelets-what-you-need-to-know-2252431
Eliquis and low platelets
https://www.medicalnewstoday.com/articles/drugs-eliquis-side-effects
~~~~
Covid vaccine and low platelets
https://medicalxpress.com/news/2021-06-covid-vaccine-linked-platelet-nationwide.html
I also understand that you were recently diagnosed with CCUS which is Clonal cytopenia of undetermined significance. This is a condition in which a person has a low blood count—a low level of certain kinds of blood cells—without an apparent cause, and a portion of the blood cells carry an acquired genetic mutation.
You had some genetics run that found 2 mutations, one of which can related to a change in your bone marrow’s ability to produce healthy blood products. Your doctor will want to monitor your bloodwork to keep an eye out for any possible trends that might signal a change. I know you’re looking for answers as to why your blood numbers are skewed so you can make changes. But it may not be from any medications or other influences that you can circumvent. Sometimes our bodies, just like a computer, can get a glitch that needs a specialist to make the correction.

Have you been referred to the hematology department at Mayo Clinic?

@j68eis There are a number of factors which can influence our blood counts at any given point whether it’s red blood cells, white blood cells or platelets. Our immune system responds to viruses, infections, vitamin/mineral deficiencies, vaccinations, medications, autoimmune diseases, cancers, etc. by increasing or reducing blood products. But they generally rebound back to normal ranges when the event has passed. Occasionally there can be something which triggers a misfire of a normal cell production. Or, it can be from a condition already at play in the body.

You mentioned in a prior comment that you’ve always had fluctuating counts throughout your life. So it’s difficult to know if your lower platelet counts can be attributed to the Eliquis you’re taking, the covid vaccine you inquired about or the infection that you had in the beginning of the year.

I found some articles you might find interesting and helpful, at least to give you more information about how and why platelet numbers fluctuate.
https://www.verywellhealth.com/living-with-low-platelets-what-you-need-to-know-2252431
Eliquis and low platelets
https://www.medicalnewstoday.com/articles/drugs-eliquis-side-effects
~~~~
Covid vaccine and low platelets
https://medicalxpress.com/news/2021-06-covid-vaccine-linked-platelet-nationwide.html
I also understand that you were recently diagnosed with CCUS which is Clonal cytopenia of undetermined significance. This is a condition in which a person has a low blood count—a low level of certain kinds of blood cells—without an apparent cause, and a portion of the blood cells carry an acquired genetic mutation.
You had some genetics run that found 2 mutations, one of which can related to a change in your bone marrow’s ability to produce healthy blood products. Your doctor will want to monitor your bloodwork to keep an eye out for any possible trends that might signal a change. I know you’re looking for answers as to why your blood numbers are skewed so you can make changes. But it may not be from any medications or other influences that you can circumvent. Sometimes our bodies, just like a computer, can get a glitch that needs a specialist to make the correction.

Have you been referred to the hematology department at Mayo Clinic?

in your comment you mentioned "one of which can related to a change in my bone marrow's
ability to produce healthy blood products" which one are yo referring to? the KM2TC or the
ASXL1 , both of which i am told have mild mutations.

Hi @j68eis You were asking questions as to why you have low platelets with consideration of the Covid vaccine or taking Eliquis. Many outside factors, including meds, illness, vaccines, etc., can lower platelets or affect other blood numbers.
You’d already relayed that your blood numbers seemed to fluctuate most of your life. So having lower platelets isn’t a new event for you. That’s why I mentioned the link between the mutated genes as possibly having more of an impact on your blood numbers than the covid vaccine.
Have you made a decision to go ahead with the Covid vaccine?