I did nothing in 2017 when diagnosed with a Gleason 6. I am now 57. In 2013 I had a small lesion on one side of my prostate which the biopsy showed was a Gleason 7. I did a HIFU procedure a couple of weeks ago and have no erectile or contenance issues. I still have Gleason 6 on the other side of my prostate. I am scheduled for a December PSA followed by a March PSA and MRI to see how effective the HIFU was. my doctor told me I did not need a biopsy every other year, and that the biopsy will just drive you to the MRI. I did have another targeted biopsy after the lesion appeared which was as much fun as the first one.