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Natural high levels of B12 and B6
Neuropathy | Last Active: Feb 17 10:25am | Replies (85)Comment receiving replies
Greetings all ,
I am new to the neuropathy thing, my feet started tingling in February, I had all the test and was diagnosed with idiopathic neuropathy, my left leg was mild my right mild to moderate . I had the b6 blood test from last week from QUESTS see below
Vitamin B6, Plasma - Quest
View trends
Normal range: 2.1 - 21.7 ng/mL
Mine 26.5
I see it is high but no idea how high it actually is in comparison, but beyond the normal range
My doctor said stop taking b complex but I don’t take any. I do take turmeric it doesn’t say b6 on the label but I read it is high-in b6. I am trying to lower my b6 and hope that helps.
Replies to "Greetings all , I am new to the neuropathy thing, my feet started tingling in February,..."
Hi @mkevin64, I would like to add my welcome to Connect along with @ray666 and others. I always look at supplements I take to see if they contain B6. Sports and energy drinks are the worse for high levels of B6 but I think it's pretty unlikely to reach high levels through intake of foods containing B6. Here are a couple of references that might be helpful:
--- The Nutrition Source - Vitamin B6: https://www.hsph.harvard.edu/nutritionsource/vitamin-b6/
--- Scientific opinion on the tolerable upper intake level for vitamin B6: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189633/
I also take turmeric but it doesn't show B6 on the ingredients. I have read that turmeric contains some B6 but not sure the kind of turmeric they are talking about - the supplement capsules or the turmeric powder or the turmeric root that you can grind up and mix with recipes. It does present an interesting question.
I also have idiopathic small fiber peripheral neuropathy and have had it over 30 years now. I posted my neuropathy journey in another discussion here - https://connect.mayoclinic.org/comment/310341/. There are also many other neuropathy discussions you might find helpful in the Neuropathy Support Group here: https://connect.mayoclinic.org/group/neuropathy/.
It sounds like you don't have any pain with your neuropathy and that is a good thing. Is the tingling the same in both feet?
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Hello, mkevin64 (@mkeven64)
I'm not a doctor. I'm a fellow with idiopathic sensory-motor peripheral neuropathy. I became enmeshed in the B6 discussion some months ago. I'm not sure I have total clarity yet. But you might want to backtrack through the posts in the thread and read what they have to say. I found one of mine, dated Sept. 14. You might want to read it (down below), then skip around, reading some of the earlier and subsequent posts.
Ray (@ray666)
Here's the post I left:
Ray Kemble | @ray666 | Sep 14 9:05am
In reply to @bb0753 "There has been some updated information since this was last updated in 2014 that indicates b6..." + (show)
Good morning. Maybe someone following these posts about B6 can help me sort something out. I understand vitamin B6 is available as pyridoxine hydrochloride in multivitamins, vitamin B-complex, and vitamin B6 supplements. My neurologist tells me that pyridoxine hydrochloride in the form of vitamin B6, if taken in excess, can lead to toxicity with its various PN-like symptoms. He assures me, however, that the form of vitamin B6 that I’m taking in EB-N5, which is pyridoxal 5’-phosphate, is essentially different; pyridoxal 5’-phosphate comes with its own dosage guardrails, but not the same toxicity concerns that accompany pyridoxine hydrochloride. Have you met this “two forms of supplemental B6” issue in anything you’ve read or been told? I have found brief mention of it in only a few places. I’d love to get some clarity. –Ray (@ray666)