Bless you for your sweet response. I've never been diagnosed with Primary Immunodeficiency but my immune system has been compromised for years.....got worse after Covid. I would think this would be why you have chronic sinusitis. I use a sinus rinse daily (NeilMed) to keep the bacteria down and hopefully to prevent another infection. I also use Cromalyn spray (it works differently than Flonase) and Astelizine - Sp? (Prescription) nasal spray for drainage. I am actually going to an Integrative Medicine Doctor and getting IV infusions to boost my puny immune system as of late. I pray that you get better and get some answers. Blessings....