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tacrolimus induced RENAL toxicity

Kidney & Bladder | Last Active: Mar 15 5:26am | Replies (22)
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@cehunt57

I started taking Prograf nearly 18 years ago for pancreas transplant. It was changed to the generic Tacrolimus because that was more cost effective. I haven’t paid attention to various “brands”. If you don’t mind sharing, why was it prescribed for you? Do you have a prescriber that monitors levels and adjusts your dose?

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Replies to "I started taking Prograf nearly 18 years ago for pancreas transplant. It was changed to the..."
l0lag0lag0b3 | @l0lag0lag0b3 | Sep 25, 2023

Initially: after the transplant .. I never paid any attention to the generic brands, until the Tacro levels started fluctuating drastically .. when a Dr Reddy brand was delivered by CVS speciality, - brought this to Doctors attention and it was recommended to keep the brand constant - I was surprised that the levels were more steady. ( I mentioned this my transplant center .. they confirmed ...stick to a brand.
In this case (accord tacrolimus) the FDA has found that toxicity caused by Accord Tacrolimus has higher than normal toxicity but it is able to maintain the Tacrolimus levels. ...
My dose is 1.5mg per day (it hasn't been adjusted over the last 3 years)

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pakyun22 | @pakyun22 | Mar 4 2:36pm

I am exactly same here, got pancreas transplant and taking prograf
recently, my kidney got really bad ,,,,stage 3 B, GFR 31
Is your kindey ok?

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