I have no personal experience with this (yet), but this sounds so difficult and excruciating for both of you! Given how much med he is having to take in order to get a little control, I would get in touch with your oncologist ASAP, at this point probably Monday morning. Be very specific about when this started and the meds and doses he's having to take in order to get just a little relief, and ask about options. Do you have a palliative care MD? At my cancer center, I was referred to a palliative doc at the same time I was referred to an oncologist. The palliative MD would likely be the one to work on pain management, I think, but if you don't have one, get your oncologist to intercede so hopefully you can get a quick appointment with the palliative MD. (I get what you're saying about the time it takes to get appointments. So frustrating!) I hope you can get some info and relief for him as quickly as possible.