I'm a male an have a similar PAC/PVC burden, around 15% overall. So far I've been prescribed Acebutolol but that has not made any impact. Cardiologist told me to follow-up in six months and seemed less concerned with the high burden. I'm going to see another cardiologist on Monday so see if they can prescribe anything else. My resting pulse is in the low 50s and noticed a slightly decrease from there when I began taking Acebutolol.