Hi, zav. I'm not able to say if the EB-N5 is helpful, not yet anyway. Unless I find that my B6 level is unacceptably high and that alarms my neurologist, I plan to continue with the EB-N5 to the end of its 90-day trial, which just happens to be the last of this month, 9/30. Oddly enough, I've never had any pain or burning with my PN (so far!), only poor balance and walking difficulty, symptoms that have not changed much since I received my PN diagnosis a little over a year ago. ––Ray