I am beginning to think my mom had this and no one told us. She lived with myelofibrosis for over 30 years and finally passed away after surgery to insert stents in both legs. She always complained her legs hurt and ached but the doctor kept dismissing her because of her age. She had 90 percent blockage in both legs! Unfortunately she did not survive the surgery because they tore her artery/vein and she slowly bled to death 21 days later.