Plaquenil and PMR

Posted by novabill @novabill, Aug 6, 2021

Recently saw a rheumatologist for the first time. Prior to seeing her I reduced to 15 mg from 20 mg of prednisone now taking 5 mg at night and 10 mg in the AM experiencing what I call background pain. Doc added 200 mg of Tylenol arthritis twice a day for pain and it has helped. Since the blood work, only the sedimentation rate was mildly elevated, she has added 200 mg Plaquenil twice a day, Tylenol arthritis as needed. I’ll add the Plaquenil tonight. I’ll see the doc in 5 weeks - goal is to further reduce the prednisone.. will let y’all know how it goes.

Interested in more discussions like this? Go to the Polymyalgia Rheumatica (PMR) Support Group.

@jfannarbor

I have had PMR off and on 30 years with an increase in prednisone (P) over that time. I was put on hydroxycholoquine (H) to reduce the P. H has worked so well that I have reduced P from 10 to 4 with no problem. Since I have had PMR for 30 years and reduce P from 10 mg to 0 maybe 15 times, but never so easily. I now think I am in remission of PMR and want to reduce P and H as fast as possible to see if I am in remission and to get off these drugs, especially H since it interferes with my sleep and gives me weird dreams. Since we all have arthritis, I am now have arthritic pain but not PMR. That is some isolated joint pain and morning stiffnesss. What are members of this blog doing for arthritic pain after being off PMR medications? I was on low dose P (2.5 mg per day) and it work well for all my pain.

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I can’t tell the difference between arthritis pain and PMR pain. To me, they’re all the same.

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@reets70

I can’t tell the difference between arthritis pain and PMR pain. To me, they’re all the same.

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I don’t know for sure since I’m new to PMR, but I think there is a muscle factor with PMR , but not with arthritis.

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@wilckdds

I don’t know for sure since I’m new to PMR, but I think there is a muscle factor with PMR , but not with arthritis.

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There is definitely muscle involvement with PMR.

Another difference is that PMR stiffness and pain generally reduces as the day goes on but arthritic pain gets worse through the day.

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@reets70

I can’t tell the difference between arthritis pain and PMR pain. To me, they’re all the same.

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The way I tell the difference between PMR and arthritis is that PMR is, for me, bi-lateral pain in my hips and shoulder girdles with fatigue for NO reason. Arthritis pain is more related to specific joints and muscles not generalized and not bi-lateral. I don't think of arthritis as associated fatigue but pain. I would love to hear from others about this distinction in my mind.

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@jfannarbor

The way I tell the difference between PMR and arthritis is that PMR is, for me, bi-lateral pain in my hips and shoulder girdles with fatigue for NO reason. Arthritis pain is more related to specific joints and muscles not generalized and not bi-lateral. I don't think of arthritis as associated fatigue but pain. I would love to hear from others about this distinction in my mind.

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I would agree @jfannarbor . I have both and my PMR after 2 yrs is diminishing and now the polyarthritis is kicking in. Arthritis Tylenol helps as I am down to 2.5 mg of Prednisone 5 days, soon to reduce to wkly. I feel my PMR lingers a little because for no reason I get fatigued. Good luck everyone!

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I developed PMR while taking Hydroxychloroquine for na-SpA ( spondylo-arthropathy). Has anyone else had this experience? What source do you use to check drug interactions?

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