Did they ever do a lymph node or bone marrow biopsy? I had an enlarged spleen and lymph nodes all over which were detected by a CT scan. It took numerous doctor visits, hospital stays and procedures (over 33 in the past year) to determine it was EBV related. Very rare and no specific treatment protocol. It affected my liver with episodes of jaundice. Just had 4 weekly infusion treatments of Rituxan which resulted in no detection of EBV. Later this month I will get another PET scan to see if nodes are reduced in size. No cure but manageable. Don’t stress over it but pursue finding a good hematologist. I didn’t have any symptoms you are having so everyone is different but I do have RA and thyroid disease. This is all autoimmune related and seems to be popping up more often now after Covid. Praying you get relief!