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← Return to Goserelin (Zoladex) 10.8mg vs Leuprolide 22.5mg: The same?
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Goserelin (Zoladex) 10.8mg vs Leuprolide 22.5mg: The same?
Prostate Cancer | Last Active: Jan 25 9:22am | Replies (2)Comment receiving replies
samidh, this paper seems to answer your question
- Comparing the Efficacy of GnRH Agonists on the Castration Levels of Metastatic Prostate Cancer; Leuprolide Acetate 22.5 mg vs. Goserelin Acetate 10.8 mg chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://cms.behmedicalbulletin.org/Uploads/Article_60185/Bagc%C4%B1larMedicalBulletin-8-150.pdf
Excerpt
"There were no statistically significant differences in achieving castration levels and the duration to reach castration levels between leuprolide 22.5 mg and goserelin 10.8 mg. "
Did your oncologist say why you were given one medication the first visit and a different the second time? Did you notice any differences?
Replies to "samidh, this paper seems to answer your question - Comparing the Efficacy of GnRH Agonists on..."
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Apologies for the delayed response; I inadvertently overlooked your post. Regarding why the medication was changed, my Onco has no answer and it's just that the hospital where I receive free treatment exhausted its supply of Zoladex. (Please don't tell them that 🙂 )
Certainly, I have noticed some distinctions. With Leuprolide, I experience higher levels of fatigue, and there is a lingering "dry-mouth" sensation for a few weeks post-injection (I keep sucking on boiled sweets). However, these variances haven't been significant enough to cause concern or bother me significantly.