Hi, Everyone-- I'll weigh in... I, too have struggled with this drug-- for all the reasons everyone is talking about and throw in hair loss, which is psychologically crushing. I'm approaching month 5 and have have only gotten to 4 clicks in that time. That's all I can take--I'm very small. I have vowed to quit Tymlos every day since April. As Windyshores knows, I'm just hoping that a half-dose will have some beneficial effect. For what it's worth to you: my current plan is to make it to 6 months, have a Dexa scan, and see where I am. If I've achieved no gains/no significant gains in that time (when gains are supposed to be the greatest), I think I will stop. I, too, am miserable on this drug but am trying to do what's best for me long-term.