Any real medical facts about Lion's Mane from a trusted source?

Thank you… am standing by!

Hi @cpttommy A search engine for you to use for medical papers or more in-depth articles on Lion’s Mane would be Google Scholar.

I typed in Lion’s Mane and there are hundreds of pages where you can do your research to make an informed decision. As with any supplements there are risks. So check with your physician before adding anything not approved by the FDA to your daily regimen.

Would you mind sharing what you hope would be the benefit from using this treatment?

Thank you for your very interesting reply. Let’s specifically what I’m looking for is treatment based on what fax there are from the national Institute of health NIH.
I want to start from the root fact of what factually Root Mane is approved for by NIH.

My intuitive training tells me that I do want to spend my time trying to find a fix for the problem first.

I don’t want to waste time on commercial ventures that are based on speculation. Most opinions are just that -opinions!

What would be very interesting is to find a mayo clinic specialized individual or team where is acting upon fax or recommendation from the NIH.

I hope I have at least attempted to clarify a logical search sequence. The American public deserves the service based on my direct contributions to the United States of America over 55 years.

Any help of your expertise is much much sincerely appreciated.

Regards, Tommy Schmitt CptTommy

Here are a few research articles on Lion's Mane.

---Lion’s Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. Suppresses H2O2-Induced Oxidative Damage and LPS-Induced Inflammation in HT22 Hippocampal Neurons and BV2 Microglia: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720269/
--- Therapeutic Potential of Hericium erinaceus for Depressive Disorder: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982118/
--- Four Weeks of Hericium erinaceus Supplementation Does Not Impact Markers of Metabolic Flexibility or Cognition: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762243/

Hi Tommy, The National Institutes of Health is an umbrella organization with many functions.

One of those is is the National Center for Complementary and Integrative Health, and one small piece of their mission is to gather and vet information about supplements. (https://www.nccih.nih.gov/health/herbsataglance) At this time, they do not have an entry for Lions Mane mushrooms

Another, and truly the most useful from a research point of view, is the National Library of Medicine, which provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health. However, most articles are scholarly publications with published credentials and citations to support the abstract. This is the information @johnbishop cited for you.

The largest function of the NIH is to support scientific and medical research with grants to universities, hospitals, non-profits and even corporations. From their home page "the agency has grown to be the world’s largest source of medical research funding and the driving force behind decades of advances that have expanded fundamental scientific knowledge and improved health."

These may be applied for and granted through any of the many "arms" of NIH, which you can see listed here: "https://www.nih.gov/institutes-nih/list-institutes-centers"

So, the best we can offer you is our research results, which John shared above. Interest in herbal medicines and supplements has exploded in the past decade - at a far faster pace than anyone can design, fund and conduct clinical studies on all of them. It seems the medical profession concentrates on those which pose the greatest potential benefit or risk to the most people. I guess Lions Mane has not made the "hit parade" yet, except for these papers we cited.
Sue

I see folks talking about this. Please share how lions mane helps ISP

thanks

@txflower2023, I moved your question to this existing discussion to help connect you with information other members have shared:
- Any real medical facts about Lion's Mane from a trusted source?
https://connect.mayoclinic.org/discussion/any-real-medical-facts-lions-mane-from-federal-source-like-nih/
You can also use the Search function to find additional discussions about Lion's Mane
https://connect.mayoclinic.org/search/discussions/?search=lion+mane

I can share my experience. I began using a quality form of Lions Mane to help with cognitive impairment from PASC. I add only one new supplement at a time to evaluate effect. I purchased my product from a long time mushroom farmer in Canada, aptly branded 'RealMushrooms." They use the 'fruiting body' not the crumbs from the stem many companies sell. This company has quality and active ingredient checks, etc. I found that this supplement did in fact perceptibly improve my cognition in only 2 weeks. I had no side effects whatsoever. I continue to take it. It's been used in Eastern Medicine for centuries. Not that that fact makes it effective or safe, but it isn't something trendy that just got the marketplace. I know my experience isn't a medical fact, but before I took this ingredient, I did due diligence research. Traditional US medicine doesn't investigate supplements to a great extent. It's not within their scope of general practice. But the bioactive material in the mushroom has properties which have been analyzed. Just FYI, you can buy these whole mushrooms as food at markets now. In case you want to expect the whole mushroom before trying the active ingredient.

No there's no facts, and Lion's Mane has been found to be an EXTREMELY DANGEROUS product which is devastating every day more lives, this is a very serious topic that should be NOT ignored, I'm the moderator of the "LionsManeRecovery" Reddit community and everyday there's new people asking for help desperately