Hello @mike02041950 @barbdk @lesliemont. Because WM is a type of blood cancer where your bone marrow produces too many abnormal white blood cells, that puts you in a higher risk for infections and diseases. The white blood cells are key figures in the immune system so when they’re defective that leaves you immunocompromised. The best defense is to go on the offense and grab those all important vaccinations such as the annual flu shot and the latest Covid booster vaccination (that one hasn’t been released yet and is due later this fall).

Here are a couple of articles which help explain why it’s a good idea and why our blood cancers put us at a higher risk.
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https://www.cancer.net/blog/2023-08/should-people-with-cancer-and-cancer-survivors-get-flu-vaccine
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https://www.cdc.gov/flu/prevent/whoshouldvax.htm
A little information from the Mayo website on WM:
https://www.mayoclinic.org/diseases-conditions/waldenstrom-macroglobulinemia/symptoms-causes/syc-20359967
Of course, it’s always a good idea to check with your oncologists to see if they recommend the vaccine for your personal care. Each of us is different but all of my doctors are on board with the added protection the shots offer.
@mike02041950 you wondered if a flu shot would skew your blood numbers. That would be a good question for your doctor.

Have you all received vaccinations in the past?