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How accurate are the PSA Tests?

Prostate Cancer | Last Active: Sep 27, 2023 | Replies (35)

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@rockin2047

Here is what I've found for you about PSA readings. The Hopkins site says "After treatment with radiation, PSA levels rarely drops completely to zero. However, the PSA should level out at a low number, which is called the nadir. When PSA rises 2 points from its lowest value, the cancer is considered recurrent." If one has had surgery it says "After surgery, PSA levels should drop to zero. When PSA levels rise above 0.2 ng/mL, the cancer is considered recurrent." Scroll down the page to the section labeled Long-Term Prognosis and read from there on down. (The source for above info is https://www.hopkinsmedicine.org/health/conditions-and-diseases/prostate-cancer/prostate-cancer-prognosis)
The next site says "The pattern of the drop in PSA after radiation therapy is also different from after surgery. PSA levels after radiation tend to drop slowly, and might not reach their lowest level until 2 years or more after treatment." Next, read the section labeled After Radiation Therapy (source is https://www.cancer.org/cancer/types/prostate-cancer/treating/psa-levels-after-treatment.html)

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Replies to "Here is what I've found for you about PSA readings. The Hopkins site says "After treatment..."

Just read the web sites what a great source of information.

I would recommend all who are wondering to read the two sites you provided.

Again also want to thank Mayo Clinic for providing this web site so us with prostrate cancer can share their experiences and information such as rockin2047 provided here.

Second that. There is too much talk about 0 PSA. Rather loose talk because they never define what 0 PSA means.