Lupron: Anyone have muscle weakness and severe leg pain?

Posted by kam23 @kam23, Jul 14, 2023

I have PC and have been on Lupron injections every 3 months for 15 months. I am experiencing severe leg pain in hamstrings and glutes. Has anyone else experienced this or tried monthly shots?

This has been getting worse for the last 3-4 weeks. I’m afraid I’ll be in a wheelchair or have to stop this form of testosterone elimination therapy.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

@frazer

Oh, in addition to the antihistamines and relative to muscle weakness I hired a trainer to work with me on resistance training. After about six sessions with him I now workout from two to three times per week for a good hour - working on upper and lower body. What I did not know about resistance training and all the machines at the fitness center would have filled a book!

In addition I consulted with a PhD Biochemist, Clinical Nutritionist who has me on a number of supplements. He also recommended I speak with my trainer to get what would be as much of a total body workout in 10 minutes as possible two to three times per day. I use a 10 lbs. medicine ball and and elastic cord with handles for five different exercises. The nutritionist advised that within the first 10 minutes after the workout I should eat a small amount of dried fruit for a high sucrose dose (three or so dried dates, cherries or apricots) and follow it with 4 ounces of liquid protein. He said the exercised muscles will up take those nutrients and actually strengthen. I'm 79 YO and am now in some of the best shape ever. Also lost 20 lbs. Good luck!

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How many days after starting Allegra did it take to start feeling better? I took one dose this morning. It’s late evening and I’m still in a lot of pain. My wife wondered if it would take a few days or so to see an improvement as some drugs take time to build up to a therapeutic level. Thanks so much for responding.

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It took 48 to 72 hours. Did you take the Allegra 24 hour? You're welcome! Good luck!

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@frazer

It took 48 to 72 hours. Did you take the Allegra 24 hour? You're welcome! Good luck!

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Got the 24 hour Allegra and took it right away. Just took my second dose…morning of day 2. Hoping for similar results to your experience. I was almost in the ER yesterday.

Thank you.

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Wow, you are having a very difficult go of it! Sorry to hear that. One thing I did not mention is that I work hard on staying hydrated. That does cause me to get up two to three times a night to urinate. Be sure you drink lots of water. May even want to add an Electrolyte like Pedialyte. You are on vitamins including calcium with magnesium correct? My PhD nutritionist has me on Now brand Red Mineral Algae Calcium 1,000 mg twice daily. He tells me it is much better absorbed than the standard CA's. Good luck on getting past this!

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My guy Russ has been taking Lupron shots also ! Leg pain in knees ! Can never get up if he has to kneel ! Has stage 4 pc metastatic in bones ! Done 6 chemos ! Taking Zytiga! Daily ! Psa is great ! He is a very strong determined man to survive ! We ride our motorcycle and enjoy life 😊 god bless u

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@hbp

I will consider a move to Thailand as it appears that you can afford to be ill and afford to die and still have money left over for a nice place in heaven with a view. Things are finally looking up. Thanks

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Thailand is a land of about 70mm and smart, very smart. Most Docs go to Ausi, USA or GB for some schooling but in the latest data, USA is #33 now in healthcare but Thailand is now #13. The Lab of the outside of the prostate ie. "On the Margin" and the two close lymph nodes showed no spread what so ever. God answered my prayers and the prayers of 400 or more people daily praying for me. The Surgeon was shocked and we were shocked. NO radiation or more Lupron shots now and just do PSA test 4 times a year and if any bump up what so ever, a PMSA Pet Scan will pinpoint in where the prostate was and outside of it too so it can be targeted exactly by Beam radiation. My odds of recurrance now are only 17% the next 10 years.

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@ddun1953

Thailand is a land of about 70mm and smart, very smart. Most Docs go to Ausi, USA or GB for some schooling but in the latest data, USA is #33 now in healthcare but Thailand is now #13. The Lab of the outside of the prostate ie. "On the Margin" and the two close lymph nodes showed no spread what so ever. God answered my prayers and the prayers of 400 or more people daily praying for me. The Surgeon was shocked and we were shocked. NO radiation or more Lupron shots now and just do PSA test 4 times a year and if any bump up what so ever, a PMSA Pet Scan will pinpoint in where the prostate was and outside of it too so it can be targeted exactly by Beam radiation. My odds of recurrance now are only 17% the next 10 years.

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Thank you for your post. So encouraging to hear success stories and faith. Made my day.

I should also note that my severe leg pain got got much worse before we finally found the cause. CT showed no problems but MRI showed that three of my vertebrae had almost completely closed off internally thereby pinching the nerves . Had back surgery a week ago and the leg pain was gone in the recovery room. Many thanks for the prayers and responses.
Muscle weakness still there but I can at least now implement the recommended strengthening exercises.

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@kam23

Thank you for your post. So encouraging to hear success stories and faith. Made my day.

I should also note that my severe leg pain got got much worse before we finally found the cause. CT showed no problems but MRI showed that three of my vertebrae had almost completely closed off internally thereby pinching the nerves . Had back surgery a week ago and the leg pain was gone in the recovery room. Many thanks for the prayers and responses.
Muscle weakness still there but I can at least now implement the recommended strengthening exercises.

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I will pray for your fast recovery bud. I only have to deal with peeing every 3 minutes now and taking a anti pee all the time pill but must take time to work.

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Thanks for the recommendations. I read the book “Starving Cancer “ and decided to combat the cancer on as many fronts as possible. Found a great Natural Pathic doctor (ND). Changed my diet. Switched to organic non processed foods. Got high dose Vitamin C infusions (100g) which in that concentration and iv creates an oxidative environment which cancer doesn’t like. Many supplements as directed by the ND. Did all this is addition to finding a great Doc at Mayo that also treated my cancer aggressively.
Keep up the good fight.

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I'm glad you brought up this topic. I was going to ask a few questions. Age here, 69, had radiation back in
March-early May. Also Eligard hormone shot. What I've noticed is tolerable, but unpleasant.
Eligard side effects, aching muscles, joints, hips, shoulders....reduced interest in things I enjoy,
fatigue...some burning while urinating, and of course, hot flashes. Anyone else have these
similar side effects? Thank you. Oh....and I almost forgot, tingling hands, arms, sore knuckles.

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