It is personalized for me specifically and the various sub-problems I have and may not work for others. It is important to identify your own triggers and have a doctor prescribe accordingly. I stopped throwing expensive supplements at my issues many years ago since most didn't work even though I really wanted them to work. Neurontin for nerve pain, a tiny spec of Klonopin for RLS, Soma for muscle pain, Mobic for inflammation (due to many ortho injuries), and Cymbalta for FM. Once we figured out tolerable doses, they have remained the same for over 20 years. It is a pretty standard combination and good for me but may not work for others. The dosages are all small.