Breast cancer treatment and kidney problems

Posted by pattykatty @crazyhazy, Oct 24, 2021

I've been on arimidex for 10 months for breast cancer, stage 2. Had lumpectomy, 30 rounds of radiation. Been on 2 other inhibitors, side effects were horrible. My onc switched me to arimidex. Besides all the side effects (joint pain, weakness, mood swings,etc) I now have problems with kidney functions. My creatinine levels and GFR scores have gone up, GFR decreased. Has anyone else have creatinine levels go up?

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@vegada

Hi Colleen,
Thanks for replying. My oncologist and nephrologist have not drawn the possible connection with arimidex but I plan to talk to both of them. I have met with a kidney dietician and that was very helpful so I am also adjusting my diet. Ironically, none of my doctors have ever brought up any possible connection to arimidex, but I am sure going to have a conversation with both of them. Maybe another aromatase inhibitor might be better because I sure don't want to progress to stage 5 Kidney failure. I am not 100% sure that Arimidex has caused my creatine to increase and I haven't found any solid medical facts indicating that it is. But I am digging into it. If you have seen any medical research on this, please let me know.

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I started an aromatase drug a month ago. For the first time, my creatinine level is high.

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@chaya242424

I started an aromatase drug a month ago. For the first time, my creatinine level is high.

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@chaya242424 welcome to connect, and the club you never wanted to join.
I would certainly be discussing this increase with my doctor, especially if it is outside normal limits. You do need to protect your kidneys while protecting yourself from the cancer.
May I ask which drug you are taking?

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