I've been on Xtandi for 7 months, Lupron at regular intervals for 9 months prior and intermitent another 4 years prior to that. The hot flashes dimnished after the first several years of Lupron.
The Xtandi is a great drug, having driven my PSA to near zero. In addition to some fatigue, I've experincd sour stomach, but diet adjustments are helping. While I was never a bear, the Xtandi has virtually elimnated body hair, excepting that on my head and face.