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Lichen planus - Who uses Tacrolimus Ointment?

Skin Health | Last Active: Aug 19, 2023 | Replies (4)

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@loribmt

Good morning, @fdixon63. I’ve been using Tacrolimus ointment to treat an area on my tongue caused by an autoimmune reaction to a stem cell transplant. I use it 2 or 3 times daily and it is a great tool for calming and healing. My transplant doctor has me use it until the area is healed and then add a couple more weeks as a good measure. I’ve also been given Dexamethasone oral rinse (30 seconds then spit out) to use in conjunction with the tacro. Those two products have made a huge difference in keeping my mouth calm.

The same autoimmune condition brought about a little area on my leg that the dermatologist coined as granuloma annular. She told me to use the Tacrolimus ointment on that area and wow, it took care of the condition in less than a week. I was instructed to use it twice daily with just a small dab rubbed in. Once it’s healed, use it 2 more weeks after that and then stop. It worked like a charm. The area is healed and never returned.
So I’m expecting you’d be having similar instructions.

The amount I use at a time is smaller than the size of a pea if that helps. (On my leg it was about lentil size) It doesn’t take much. Think of it as a medicated Vaseline…a little goes a long way. Just rub it in really well for a few seconds and you’re good to go.

Tacrolimus is an anti-inflammatory medication and used for many applications such as pill, injection or IV form as an anti-rejection med for transplant patients. It also works very well when applied topically in an ointment to calm psoriasis, eczema, lichen planus, granuloma annular and a host of other skin conditions.
Prograf is the trademark name of tacrolimus. The ointment is often called Protopic.
There are quite a few references in the forum in various groups with members who use the tacrolimus/Protopic ointment.

I’ve posted one link below.

~Erosive oral lichen planus
Reply by @artist01 regarding her use of Protopic ointment
https://connect.mayoclinic.org/comment/633127/
From this dicussion on Erosive Oral Lichen Planus
https://connect.mayoclinic.org/discussion/erosive-oral-lichen-planus/
You can type any any of those words…Tacrolimus Ointment. Prograf Ointment or Protopic and a host of other conversations will pop up for you.

Hopefully this tacro ointment brings you some relief. I know it has worked miracles for me.

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Replies to "Good morning, @fdixon63. I’ve been using Tacrolimus ointment to treat an area on my tongue caused..."

Hi Lori. Thanks so much for the wealth of information. I did a little reading about the ointment last night and I think it warned against using in the mouth but sounds like it was OK'd by your doctor to use there--right? I've just got my first upper partial a couple of weeks ago and because of the tender LP gums it is not fun. Now I wonder if I could use Tacrolimus on those places? Guess I should clarify with my derm doc. Will go through the sites you listed later on. I was in a car accident at noon today and had to stay for an hour and a half as there were three cars involved. Also it was 100 degrees. I think I'm OK but will probably be sore tomorrow. Thanks again for this information. Faye