I have a very high calcium score. What next?

Posted by dpframing @dpframing, Aug 24, 2018

Just joined the site and I'm looking to share with others who have had a high calcium score. I found out today that mine is 2996 and I am scared by this. I am 61 and I am totally asymptomatic. Now I feel like a walking time bomb. I am thinking of requesting an angiogram to see if there's any narrowing anywhere and if it can be corrected with a stent. After a second heart doctor told me that the plaque buildup might be uniform over the course of years with no big problem areas, I am encouraged. But the score still freaks me out, specifically my LAD at 1333. I don't smoke or drink but I have to lose 40 lbs.

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@sjy70

If you are looking to interview anyone for this article, please reach out to me. I’d love to include my thoughts. Private message me for my details.

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Hi @sjy70. You may notice I edited your post to remove your email and changed it to "private message me." Mayo Clinic Connect is a public site and we don't want our members to get spam mail from unwanted solicitors so we encourage you to not share private contacts in the public post. Sharing via private message will keep your information private between you and whoever you are communicating with.

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@mayoconnectuser1

deb,

Agree with christian, above. While better, you should probably get you LDL and total cholesterol much lower. Many report good results from injectable's to lower both.

- advanced lipids panel done, called cardioiq by some
- stress test with ultrasound should have been one of first things

You don't mention your triglycerides ... need to reduce, as well.

You have taken action to repair damage done by known risks - please keep working it!

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Thank you for the comments, I should have mentioned that all my stress tests have been exemplary. My triglycerides are normal and my HDL is 59. I have been plagued with anxiety the last 10 years (PTSD) and this CAC score seems to trigger it! I am trying to put it in the “informative” category, however anytime I feel something weird in my chest I become so anxious not knowing if that is a precursor to something bigger. Has anyone tried the red yeast rice as a natural cholesterol reducer?

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So, given numbers are important to avoid misunderstanding, your stress tests (you don't say if they had an "echo" component which is recommended with heart disease) should have provided some scoring - like a METS number.

And, same point wrt triglycerides - what number?

My sense is that many folks reporting in on this forum have forced their cholesterol to around 100, and their LDL and triglycerides to around 50 ... usually with a statin, better eating, and perhaps icosapent ethyl.

Re red yeast rice - here's a link to a Mayo article -https://www.mayoclinic.org/drugs-supplements-red-yeast-rice/art-20363074

Here' what it said - please note the specific warning on drinking alcohol with red yeast rice.

"Overview

Red yeast rice is the product of yeast (Monascus purpureus) grown on white rice. The powdered yeast-rice mixture is a dietary staple in Asia and has been used in traditional Chinese medicine.

Red yeast rice is also available as an oral supplement.

Red yeast rice might contain compounds that appear to lower cholesterol levels. One of the compounds is monacolin K, the same ingredient that is in the prescription cholesterol-lowering drug lovastatin (Altoprev).

As an oral supplement, people take red yeast rice for high cholesterol and heart disease.

What the research says

Research on red yeast rice use for specific conditions shows:

High cholesterol (hyperlipidemia). Research shows that red yeast rice containing considerable amounts of monacolin K can lower your total blood cholesterol level, your low-density lipoprotein (LDL, or "bad") cholesterol level and your triglyceride level.
Our take

Yellow light: Caution
Caution

Red yeast rice is capable of lowering blood cholesterol levels and total blood cholesterol levels. While the supplement is generally considered safe, it might carry the same potential side effects as statin cholesterol drugs.

Red yeast rice might cost less than a statin. However, with a supplement, there's less assurance regarding quality and how much active ingredient is actually in the product. Some red yeast products might contain only small amounts of monacolin K and potentially have little effect on cholesterol levels.

Safety and side effects

Red yeast rice can cause mild side effects, including:

Abdominal discomfort
Heartburn
Gas
Headache
Dizziness
Red yeast rice might contain monacolin K, the same ingredient that is in the prescription cholesterol-lowering drug lovastatin. Lovastatin side effects include liver damage and muscle disorders (myopathy).

Don't take red yeast rice if you're pregnant, trying to become pregnant or breast-feeding.

An older study raised the concern that some red yeast rice products contain a contaminant called citrinin, which can cause kidney failure. However, a more recent study that analyzed 14 red yeast rice dietary supplements didn't find citrinin in any of them.

Interactions

Possible interactions include:

Alcohol. Don't drink alcohol if you are taking red yeast rice. The combination might increase the risk of liver damage.
Cyclosporine (Neoral, Sandimmune). Taking this immunosuppressive drug with red yeast rice might increase the risk of myopathy.
Cytochrome P450 3A4 (CYP3A4) inhibitors. Taking red yeast rice with drugs, such as erythromycin, that inhibit this enzyme might increase the risk of harmful red yeast rice side effects.
Grapefruit. Drinking grapefruit juice and taking red yeast rice might increase the risk of the supplement's harmful side effects.
Gemfibrozil (Lopid). Taking this cholesterol drug with red yeast rice might increase the risk of myopathy.
Hepatotoxic drugs, herbs and supplements. Red yeast rice might contain monacolin K, which can cause liver damage in some people. Taking red yeast rice with these types of drugs, herbs and supplements could increase the risk of liver damage.
Niacin. Taking red yeast rice with high-dose niacin might increase the risk of myopathy.
St. John's wort. Taking this supplement with red yeast rice might reduce the effectiveness of red yeast rice.
Statin. Taking red yeast rice with other statins might increase the risk of harmful side effects."

Perhaps consider changing to a different statin, or an injectable that avoids the side effects of oral statins, but has less potential side effects and is more "pure" than OTC red yeast rice?

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@christianzane

A CAC score is just informing you about your arterial health. Soft plaque (which is usually the stuff that will get you in the end) doesn’t show up on a CAC score, but what lights up is the hardened calcification. Since a high CAC score is a proven predictor of increased CAD events, it should just be used as a guide to make lifestyle changes. My doctor has told me repeatedly he has patients in their 90s with CAC score in the 1000s.

Elevated CAC scores have also been associated with increased risk of other noncardiovascular diseases including cancer, kidney disease and obstructive pulmonary disease.

So a high CAC score is not a death sentence. It’s just an informative tool to nudge many of us into a healthier lifestyle. And your LDL still seems on the high side, ideally get it under 70, if you had issues with a statin before try another manufacturer and lower dose and try to ride out any muscle spasms for a few months to see if they go away.

So any of us with calcified arteries should just go about our lives but make necessary lifestyle choices and forget about it. Exercise, quality sleep, low blood pressure, minimal stress, a plant based diet when possible, a statin to lower LDL and no smoking are simple ways to live to 100 with a high CAC score.

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Well put @christianzane! I'm still struggling to mentally get past the original diagnosis from June, but I've dropped from 250 to 228lbs, I jog/walk 2 miles a day, take a statin and aspirin (with some muscle spasms during long drives) and eating a med. based diet. I'm still needing guidance from a nutritionist as there are many perspectives on how we should be eating, but so far low carb and low fat is getting the weight off and I'm starting to come off blood pressure meds too. I think it isn't stated enough that your risk is greatly reduced if you follow the 7 things you state in your post. Really, your risk is very close to that of the general population if not better because you will be in such great physical shape and other causes of disease and death will also be greatly reduced.

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@tylindy

Well put @christianzane! I'm still struggling to mentally get past the original diagnosis from June, but I've dropped from 250 to 228lbs, I jog/walk 2 miles a day, take a statin and aspirin (with some muscle spasms during long drives) and eating a med. based diet. I'm still needing guidance from a nutritionist as there are many perspectives on how we should be eating, but so far low carb and low fat is getting the weight off and I'm starting to come off blood pressure meds too. I think it isn't stated enough that your risk is greatly reduced if you follow the 7 things you state in your post. Really, your risk is very close to that of the general population if not better because you will be in such great physical shape and other causes of disease and death will also be greatly reduced.

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Thank you and don't stress, in people aged 30–70 years old, 25% have vascular calcification.

In people aged over 70 years old, 90% of men and 67% of women have coronary artery calcification.

This is just like HPV. 90% of the population will get HPV. Get a test for it and panic? Of course not. CAC score is different obviously as HPV eventually resolves itself. But you can stabilize the existing plaque, greatly slow the progression of new plaque and go on with your life with dietary and lifestyle modifications.

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@debwellmadebeh

I am in the same boat, 60 yr. Old female, have always been healthy, CAC of 585, (472 in my LAD) of my total score, statins have not agreed with me at all, I am doing red yeast rice 600 mg/day, my chol. numbers have decreased in 6 weeks, cholesterol is 201 down from 238, LDL 126, down from 151, I walk 36 miles a week and quit smoking 8 weeks ago, and cut out diary. I wish I had never taken the test, I live in fear of a cardiac event daily (certainly no way to live). I asked my cardiologists if we should do a cath or stent, he said no, Cath’s are too dangerous and no symptoms to indicate needing a stent, sadly when you have symptoms it might be too late. There seems to be a big void in testing AFTER the calcium test to know if you are actually okay. They don’t want you to repeat the test, but they say the score can only get worse, it cannot decrease no matter what medications you take. The scary thing is that you can hopefully keep it from progressing but if you are already at a “high risk” level you just feel like a walking time bomb, there has to be a better way to test patients at high risk levels on a monthly basis so that we don’t live in fear. Does improving your numbers really help? I have seen where people have normal Chol. numbers but have high CAC scores, and no real explanation. Also, testing for hard plaque versus soft plaque would be helpful after you get a high CAC score. I really enjoy this forum as I find it very informative hearing from others that are enduring the same health issues. Has anyone had good results from the red yeast rice?

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Sorry you're living in daily fear. I cannot say I am but it seeps into my mind every few days. I'm a fatalist. I do all I can to help my heart....swim, take the right drugs, try to lose weight etc....and if it's not enough, well, then it's not enough. I try to put it out of my mind. But obviously I'm still here and find this forum helpful as well so it's not totally out of my mind 🙂

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@writer418

I tried Prluent and my LDL plunged as did overall cholesterol numbers. of course then my insurance stopped paying so I’ve switched to Repatha which is I’m told similar. Whatever you do, I’ve listened and read a lot of info about this including this board which I too enjoy. From what I’ve discovered, the best treatment is a combo of statins and a PSK9 inhibitor like Praluent or Repatha and I believe Leqvio is in that category. I’m a journalist and am soon going to write an article about the stress caused by people having this test. I wish I had never taken it. It’s changed my outlook about my own health and I’m not really sure it means anything. Statins, which I’ve taken for years, are designed to calcify plaque so it’s not dangerous. So does the fact that my score is 642 (my wife’s is 0 and she has not taken statins) mean I’m somehow at risk? I’m not convinved.

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If/when you write your article could you please share link to it. The added daily stress form this test cannot be a good thing overall...and yet impossible to 'unknow' the results.
Thank you

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I have been setting calcium score records for decades now. 5400 when I was your age...8000 now at 78. The key is profusion or dispersion over many years and the hardness of the plaque. Don't fret about narrowing . Just listen to your own opinion of well-being. For people like us with a lot of calcium deposits, the calcium score is a big distraction and worrier. Too much data, not much information or guidance. I'm not saying we're not candidates for issues down the road, but that road can be pretty long and pretty enjoyable. Of course, consider your diet and exercise routines.
Finally, I've found intermittent fasting to be a miracle worker. Lost weight, no joint pain, etc. etc.
Again, be guided by how you feel.

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@pumaguy79 At a CAC score of 8000, did you ever need a stent? Have you ever felt any chest pain? That's quite a score! My score this past March was 2534 (at 61 years of age). Absolutely asymptomatic at this point. I consider myself pretty fit for my age. I walk about a mile 5-6x a week, exercise every other day (sandbag training), mostly vegetarian, no alcohol, no smoking. I was put on 20mg Crestor/Rosuvastatin shortly after receiving my score and started taking D3, K2 and CoQ10 shortly after receiving my score. I chose NOT to go on a baby aspirin though due to the risk of stroke, brain hemorrhage and stomach ulcers.

Just curious how you feel with a score that high.

Thanks,

Andy

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@cianci

In some ways I too wish I had not gotten the test. No one can adequately explain what it means.
My cardiologist says my score didn't go to 3500 overnight, I figure I was over 400 (very high risk) for over 10 years. So I am overdue for a heart event. What a way to live.
My health has deteriorated since because I can't tolerate rosuvastatin, now down to 5mg but still have aches in the buttocks and legs.
On the other hand, I don't want to dismiss conventional medical thinking.

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Hello

Yes sometimes diagnosis itself can be another disease! Calcium score would just mean be more watchful in your life style. It shouldn’t drive you with fear and hence over treatment.
I as a cardiologist was supposed to give a talk on calcium score to the drs of my city, when I casually checked mine : 746!
No symptoms no risk factors. Nuclear test was done and was fine. That was 4 years ago. Now I am 57.
I take rosuvastatin 20 a day and I jog about 60 miles a month. ( one half marathon every month, in around 2 hrs 15 min)

I did have butterflies for few months and slowly I have reduced thinking about it.

Best wishes to all🌱🌱👍

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