Hi All,
I am responding to Justin's request for comment on responces to Prolia treatment. So far, I have only had 2 shots of Prolia, so my input is not "time tested".
Also, I have a few medical conditions that have the miserable symptom of fatigue. My fatigue levels, which can be severe, have not shown any difference with the addition of Prolia.
Sadly, it seems there is not a deep understanding of fatigue; the causes or the cure. Hopefully, you have understanding and patient supports.
My sympathies to all who are waylaid by this problem.

I am replying to this post because of your invitation.

I did not experience fatigue from my five Prolia injections over two and a half years. I did discontinue Prolia primarily because I feel it caused extreme hair loss. I cannot prove this but Amgen (manufacturer) admits there were reports of hair loss after product went to market.

I also developed a chronic sore throat after my first injection. I’ve been diagnosed with LPR (acid issue) so maybe unrelated but the timing makes me suspicious.

I am now taking Evista, prescribed by process of elimination. There is a risk of blood clots with this medication but my endocrinologist felt comfortable with it as I have not had clots in the past.

I also take supplements for hair, bones, etc.

Not due for a scan until next year, but I’ll post at that time.

Best wishes to all regarding this seemingly complicated condition. Cindy

I have not been on any other osteo drugs and the reason why he wants to add the Prolia is that my Dexascan showed my hip to be 78 and also my recurrent prostate cancer (for which I had three sessions of radiation were to a vertebrae and rib. There has been no indication of any cancer in my hip or spine and my PSA an tertosterone are both unmeasurable after the 6 moths of Eligard and Erleada