My mother (now 87) was diagnosed about 4 years ago and was in smoldering stage. Now we believe she is in stage 1 (but we can't get straight answers from her dr who said MM is not staged). Anyway, she tried revlimid but had horrible side effects - horrendous rash. She is now on Isatuximab. She did one month every week, then two months every other week, and is now on 1x a month. Her side effects last about one week - fatigue, dizziness, brain fog, some nausea. Her kappa light chains started at 425, then went down during weekly treatment to 386, and now is up to 433 on monthly treatment. Her other numbers look good. Her dr says not to worry about the 433. We have no idea if 433 is super high or what. Really can't get straight answers from dr. Any insights appreciated.