Hello - I have been on Cimzia injections and injectable Methotrexate for a handful of years. This combo did stop the joint damage for me and has been working well. I have had 1 flare that required a steroid taper since being on this combo for RA and UC. It gave me my life back (was life changing). Cimzia is similar to Humira. I could not afford this without the help of the co-pay program the pharmaceutical company offers and insurance from my employer. That is not to say I still don't have side affects of the disease but my pain is much better controlled. I hope this information is helpful to someone. I'm happy to share my story and what has worked for me.