I am sorry your husband is experiencing pleural effusion while taking Ibrutinib. I was on Ibrutinib for just over two years and did not experience p.e. I strongly recommend the IWMF Lifeline list - https://iwmf.com/wp-content/uploads/2022/12/IWMF_LIFELINE-1-1.pdf
You can communicate with one of the Ibrutinib contacts and the Pleural Effusion contact person. They have personal experience along with communications with other IWMF members.
If you need further assistance with the above link, I would be happy to direct you. ( I am a support group co-leader for the I.W.M.F. - International Waldenstrom’s Macroglobulinemia Foundation.)
Please keep us posted and know that we care and support you.